Preheat oven to 325°F (165°C).
In a medium bowl, combine graham cracker crumbs, sugar, and butter. Press into the bottom of a greased 9-inch springform pan. Bake for 12 minutes.
In a large mixing bowl, beat together cream cheese, sugar, and vanilla until smooth. Add in eggs, one at a time, beating well after each addition. Add in mango puree and mix until well combined. Pour into crust.
Bake 75 to 85 minutes, until the center is almost set. Cool, cover, and chill overnight.
Garnish suggestion: fresh mango wedges.